A Mathematical Approach Using Strat-M^® to Predict the Percutaneous Absorption of Chemicals under Finite Dose Conditions

• Main Authors: Ryoki Kunita (Author), Takafumi Nishijima (Author), Hiroaki Todo (Author), Kenji Sugibayashi (Author), Hitoshi Sakaguchi (Author)
• Format: Book
• Published: MDPI AG, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Estimation of the percutaneous absorption is essential for the safety assessment of cosmetic and dermopharmaceutical products. Currently, an artificial membrane, Strat-M^®, has been focused on as the tool which could obtain the permeation parameters close to the skin-derived va...