Joint effects of polycyclic aromatic hydrocarbons, smoking, and XPC polymorphisms on damage in exon 2 of KRAS gene among young coke oven workers

• Main Authors: Siqin Chen (Author), Xingyue Yin (Author), Yuefeng He (Author), Qinghua He (Author), Xiaomei Li (Author), Maosheng Yan (Author), Suli Huang (Author), Jiachun Lu (Author), Binyao Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Genetic polymorphisms may contribute to individual susceptibility to DNA damage induced by environmental exposure. In this study, we evaluate the effects of co-exposure to PAHs, smoking and XPC polymorphisms, alone or combined, on damage in exons. A total of 288 healthy male coke oven workers were e...