Targeting JAK2/STAT3, NLRP3/Caspase-1, and PK2/PKR2 Pathways with Arbutin Ameliorates Lead Acetate-Induced Testicular Injury in Rats

• Main Authors: Hany H. Arab (Author), Shuruq E. Alsufyani (Author), Ahmed M. Ashour (Author), Amany M. Gad (Author), Alzahraa A. Elhemiely (Author), Mohamed H. A. Gadelmawla (Author), Marwa Ahmed Mahmoud (Author), Ali Khames (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The reproductive system of males is adversely impacted by lead (Pb), a toxic heavy metal. The present study examined arbutin, a promising hydroquinone glycoside, for its potential ameliorative impact against Pb-induced testicular impairment in rats. The testicular injury was induced by the intraperi...