Neopentyl glycol-based radiohalogen-labeled amino acid derivatives for cancer radiotheranostics

• Main Authors: Yuta Kaizuka (Author), Hiroyuki Suzuki (Author), Tadashi Watabe (Author), Kazuhiro Ooe (Author), Atsushi Toyoshima (Author), Kazuhiro Takahashi (Author), Koichi Sawada (Author), Takashi Iimori (Author), Yoshitada Masuda (Author), Takashi Uno (Author), Kento Kannaka (Author), Tomoya Uehara (Author)
• Format: Book
• Published: SpringerOpen, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background L-type amino acid transporter 1 (LAT1) is overexpressed in various cancers; therefore, radiohalogen-labeled amino acid derivatives targeting LAT1 have emerged as promising candidates for cancer radiotheranostics. However, 211At-labeled amino acid derivatives exhibit instability a...