Carboxylesterase 2 induces mitochondrial dysfunction via disrupting lipid homeostasis in oral squamous cell carcinoma

• Main Authors: Xijuan Chen (Author), Qin Liu (Author), Yingyao Chen (Author), Lixuan Wang (Author), Rongchun Yang (Author), Weilin Zhang (Author), Xue Pan (Author), Siyuan Zhang (Author), Chuwen Chen (Author), Tong Wu (Author), Juan Xia (Author), Bin Cheng (Author), Xiaobing Chen (Author), Xianyue Ren (Author)
• Format: Book
• Published: Elsevier, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Oral squamous cell carcinoma (OSCC) is characterized by high recurrence and metastasis and places a heavy burden on societies worldwide. Cancer cells thrive in a changing microenvironment by reprogramming lipidomic metabolic processes to provide nutrients and energy, activate oncogenic si...