Potential drug development candidates for human soil-transmitted helminthiases.

• Main Authors: Piero Olliaro (Author), Jürg Seiler (Author), Annette Kuesel (Author), John Horton (Author), Jeffrey N Clark (Author), Robert Don (Author), Jennifer Keiser (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Few drugs are available for soil-transmitted helminthiasis (STH); the benzimidazoles albendazole and mebendazole are the only drugs being used for preventive chemotherapy as they can be given in one single dose with no weight adjustment. While generally safe and effective in reducing intensity of in...