Tetramethylpyrazine Analogue T-006 Protects Neuronal and Endothelial Cells Against Oxidative Stress via PI3K/AKT/mTOR and Nrf2 Signaling

• मुख्य लेखकों: Guiliang Zhang (लेखक), Zirong Liang (लेखक), Yuqiang Wang (लेखक), Zaijun Zhang (लेखक), Pui-Man Hoi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2024-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: T-006, a novel neuroprotective derivative of tetramethylpyrazine (TMP), exhibits multifunctional neuroprotective properties. T-006 has been shown to improve neurological and behavioral functions in animal models of ischemic stroke and neurodegenerative diseases. The present study aims to...