Low-dose mitotane-induced neurological and endocrinological complication in a 5-year-old girl with adrenocortical carcinoma

• Main Authors: You Joung Heo (Author), Jae Ho Yoo (Author), Yun Soo Choe (Author), Sang Hee Park (Author), Seung Bok Lee (Author), Hyun A Kim (Author), Jung Yoon Choi (Author), Young Ah Lee (Author), Byung Chan Lim (Author), Hee Won Chueh (Author)
• Format: Book
• Published: Korean Society of Pediatric Endocrinology, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mitotane is an adrenolytic drug that exhibits therapeutic effects within a narrow target range (14-20 μg/dL). Various complications develop if the upper limit is exceeded. We present the case of a 5-year-old girl with breast development, acne, and pubic hair who was diagnosed with an adrenal mass th...