Designing, synthesis and bioactivities of 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamides

• Egile Nagusiak: Halise Inci Gul (Egilea), Ebru Mete (Egilea), Sakip Emre Eren (Egilea), Hiroshi Sakagami (Egilea), Cem Yamali (Egilea), Claudiu T. Supuran (Egilea)
• Formatua: Liburua
• Argitaratua: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

In this study, 4-[3-(4-hydroxyphenyl)-5-aryl-4,5-dihydro-pyrazol-1-yl]benzenesulfonamide (1-9) types compounds were synthesized and their chemical structures were confirmed by 1H NMR, 13C NMR and HRMS spectra. Cytotoxic and carbonic anhydrase (CA) inhibitory effects of the compounds were investigate...