Does prior dengue virus exposure worsen clinical outcomes of Zika virus infection? A systematic review, pooled analysis and lessons learned.

Does prior dengue virus exposure worsen clinical outcomes of Zika virus infection? A systematic review, pooled analysis and lessons learned.

Zika virus (ZIKV) recently caused a pandemic complicated by Guillain-Barre syndrome (GBS) and birth defects. ZIKV is structurally similar to the dengue viruses (DENV) and in vitro studies suggest antibody dependent enhancement occurs in ZIKV infections preceded by DENV; however, the clinical signifi...

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Main Authors: Jennifer Masel (Author), Michael K McCracken (Author), Todd Gleeson (Author), Brian Morrison (Author), George Rutherford (Author), Allison Imrie (Author), Richard G Jarman (Author), Michael Koren (Author), Simon Pollett (Author)
Format: Book
Published: Public Library of Science (PLoS), 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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