The NALP3/Cryopyrin-Inflammasome Complex is Expressed in LPS-Induced Ocular Inflammation

• Main Authors: José F. González-Benítez (Author), Marco A. Juárez-Verdayes (Author), Sandra Rodríguez-Martínez (Author), Mario E. Cancino-Diaz (Author), Francisco García-Vázquez (Author), Juan C. Cancino-Diaz (Author)
• Format: Book
• Published: Hindawi Limited, 2008-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In the inflammosome complex, NALP3 or NALP1 binds to ASC and activates caspase-1 which induces IL-1β. In murine LPS-induced ocular inflammation, the production of IL-1β is increased. We suggest that NALP3- or NALP1-inflammasome complex can be participating in the LPS-induced ocular inflammation. In...