Detection of subtelomere imbalance using MLPA: validation, development of an analysis protocol, and application in a diagnostic centre

• Main Authors: Hills Alison (Author), Madula Rajiv (Author), Thomas Helen (Author), Welch Alysia (Author), Mackie Ogilvie Caroline (Author), Ahn Joo Wook (Author), Donaghue Celia (Author), Mann Kathy (Author)
• Format: Book
• Published: BMC, 2007-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Commercial MLPA kits (MRC-Holland) are available for detecting imbalance at the subtelomere regions of chromosomes; each kit consists of one probe for each subtelomere.</p> <p>Methods</p> <p>For validation of...