Preparation and immunoprotective effects of a virus-like particle candidate vaccine of the dominant epidemic D3 genotype coxsackievirus A6 in China

• Main Authors: Xiaoliang Li (Author), Xizhu Xu (Author), Jichen Li (Author), Huanhuan Lu (Author), Congcong Wang (Author), Rui Wang (Author), Jinbo Xiao (Author), Ying Liu (Author), Yang Song (Author), Jingdong Song (Author), Qiang Sun (Author), Yong Zhang (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Coxsackievirus A6 of the D3a genotype (CVA6 D3a) is a primary pathogen causingmainland of China's hand, foot, and mouth disease (HFMD). Viral-like particle (VLP) vaccines represent a potential candidate vaccine to prevent HFMD. This study collected Anti-CVA6 D3a VLPs serum from BALB/c female mi...