The obesity gene, TMEM18, is of ancient origin, found in majority of neuronal cells in all major brain regions and associated with obesity in severely obese children

• Main Authors: Levine Allen S (Author), Sreedharan Smitha (Author), Alsiö Johan (Author), Cedernaes Jonathan (Author), Olszewski Pawel K (Author), Shaik Jafar HA (Author), Jacobsson Josefin A (Author), Almén Markus (Author), Fredriksson Robert (Author), Marcus Claude (Author), Schiöth Helgi B (Author)
• Format: Book
• Published: BMC, 2010-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>TMEM18 is a hypothalamic gene that has recently been linked to obesity and BMI in genome wide association studies. However, the functional properties of TMEM18 are obscure.</p> <p>Methods</p> <p>The evolutiona...