Role of ErbB receptors in cancer cell migration and invasion

• Main Authors: Aline eAppert-Collin (Author), Pierre eHubert (Author), Gerard eCremel (Author), Amar eBennasroune (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Growth factors mediate their diverse biologic responses (regulation of cellular proliferation, differentiation, migration and survival) by binding to and activating cell-surface receptors with intrinsic protein kinase activity named Receptor Tyrosine Kinases (RTKs). About 60 RTKs have been identifie...