Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p

• Main Authors: Jin-Jin Song (Author), Hui Li (Author), Nan Wang (Author), Xiao-Yan Zhou (Author), Yan Liu (Author), Zhen Zhang (Author), Qian Feng (Author), Yu-Ling Chen (Author), Dan Liu (Author), Jia Liang (Author), Xiang-Yu Ma (Author), Xiang-Ru Wen (Author), Yan-Yan Fu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Neuroinflammation plays a pivotal role in the pathogenesis of Central Nervous System (CNS) diseases. The phenolic glucoside gastrodin (GAS), has been known to treat CNS disorders by exerting anti-inflammatory activities. Our aim was to investigate the potential neuroprotective mechanisms...