Calotropis gigantea extract induces apoptosis through extrinsic/intrinsic pathways and reactive oxygen species generation in A549 and NCI-H1299 non-small cell lung cancer cells

• Main Authors: Jiyon Lee (Author), Hui-Ju Jang (Author), Hyunwoo Chun (Author), Thu-Huyen Pham (Author), Yesol Bak (Author), Jong-Woon Shin (Author), Hang Jin (Author), Yong-In Kim (Author), Hyung Won Ryu (Author), Sei Ryang Oh (Author), Do-Young Yoon (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Calotropis gigantea (CG) is a tall and waxy flower that is used as a traditional remedy for fever, indigestion, rheumatism, leprosy, and leukoderma. However, the precise mechanisms of its anticancer effects have not yet been examined in human non-small cell lung cancer (NSCLC) ce...