Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth

• Auteurs principaux: Xianglan Yi (Auteur), Mengxin Qi (Auteur), Mingxiang Huang (Auteur), Sheng Zhou (Auteur), Jing Xiong (Auteur)
• Format: Livre
• Publié: Frontiers Media S.A., 2022-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Background: Hypoxia-inducible factor-1α (HIF-1α) induces the expression of glycolysis-related genes, which plays a direct and key role in Warburg effect. In a recent study, honokiol (HNK) was identified as one of the potential agents that inhibited the HIF-1α signaling pathway. Because the HIF- 1α p...