6'-Hydroxy Justicidin B Triggers a Critical Imbalance in Ca2+ Homeostasis and Mitochondrion-Dependent Cell Death in Human Leukemia K562 Cells

Justicia procumbens (J. procumbens) is a traditional Chinese herbal medicine which was used for the treatment of fever, pain, and cancer. A compound 6'-hydroxy justicidin B (HJB) isolated from J. procumbens exhibits promising biological properties. However, the mechanism of action and the in vi...

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Main Authors: Jiaoyang Luo (Author), Jiaan Qin (Author), Yanwei Fu (Author), Shanshan Zhang (Author), Xingguo Zhang (Author), Meihua Yang (Author)
Format: Book
Published: Frontiers Media S.A., 2018-06-01T00:00:00Z.
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