Synthesis and PASS-assisted in silico approach of some novel 2-substituted benzimidazole bearing a pyrimidine-2, 4, 6(trione) system as mucomembranous protector

Purpose: The present paper demonstrates the utility of PASS computer-aided program and makes a clear comparison of predicted and observed pharmacological properties of some novel 5-[(2E)-1-(1H-benzimidazol-2-yl)-3-substituted phenylprop-2-en-1-ylidene] pyrimidine-2, 4, 6 (1H, 3H, 5H)-triones (5a-f)....

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Hoofdauteurs: Bijo Mathew (Auteur), Jerad Suresh (Auteur), Socklingam Anbazhagan (Auteur)
Formaat: Boek
Gepubliceerd in: Wolters Kluwer Medknow Publications, 2013-01-01T00:00:00Z.
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