A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome.

Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L. braziliensis pathogenesis or response to chemotherapy in vivo due to the natural resistance of most mou...

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Main Authors: Adriano C Coelho (Author), Jordana C Oliveira (Author), Caroline R Espada (Author), Juliana Q Reimão (Author), Cristiana T Trinconi (Author), Silvia R B Uliana (Author)
Format: Book
Published: Public Library of Science (PLoS), 2016-05-01T00:00:00Z.
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