Hepatic stellate cell reprogramming via exosome-mediated CRISPR/dCas9-VP64 delivery
Hepatic stellate cells (HSCs) play a crucial role in the progression of liver fibrosis, which can be considered as the specific therapeutic target of anti-fibrotic treatment. Targeted induction of HSCs to hepatocytes via delivery of clustered regularly interspaced short palindromic repeats (CRISPR)/...
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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