Fractional laser-assisted topical delivery of bleomycin quantified by LC-MS and visualized by MALDI mass spectrometry imaging

• Κύριοι συγγραφείς: Kristoffer K. Hendel (Συγγραφέας), Charlotte Bagger (Συγγραφέας), Uffe H. Olesen (Συγγραφέας), Christian Janfelt (Συγγραφέας), Steen H. Hansen (Συγγραφέας), Merete Haedersdal (Συγγραφέας), Catharina M. Lerche (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Bleomycin exhibits antiproliferative effects desirable for use in dermato-oncology but topical use is limited by its 1415 Da molar mass. Ablative fractional laser (AFL)-assisted drug delivery has been shown to enhance drug uptake in skin. The aim of this study was with AFL to deliver bleomycin into...