Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• المؤلفون الرئيسيون: Ki-Sun Park (مؤلف), Hyungjun Kim (مؤلف), Hye Jin Kim (مؤلف), Kang-In Lee (مؤلف), Seo-Young Lee (مؤلف), Jieun Kim (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2022-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...