Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• Autors principals: Ki-Sun Park (Autor), Hyungjun Kim (Autor), Hye Jin Kim (Autor), Kang-In Lee (Autor), Seo-Young Lee (Autor), Jieun Kim (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2022-03-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...