Paeoniflorin Alleviates Skeletal Muscle Atrophy in Ovariectomized Mice through the ERα/NRF1 Mitochondrial Biogenesis Pathway

• मुख्य लेखकों: Ki-Sun Park (लेखक), Hyungjun Kim (लेखक), Hye Jin Kim (लेखक), Kang-In Lee (लेखक), Seo-Young Lee (लेखक), Jieun Kim (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2022-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Muscle atrophy in postmenopausal women is caused by estrogen deficiency and a variety of inflammatory factors, including tumor necrosis factor alpha (TNFα). Paeoniflorin (PNF), a natural compound with anti-inflammatory properties, improves estradiol synthesis. Here, we demonstrate that PNF inhibits...