Identification of novel GNAS mutations in intramuscular myxoma using next-generation sequencing with single-molecule tagged molecular inversion probes

• Main Authors: Elise M. Bekers (Author), Astrid Eijkelenboom (Author), Paul Rombout (Author), Peter van Zwam (Author), Suzanne Mol (Author), Emiel Ruijter (Author), Blanca Scheijen (Author), Uta Flucke (Author)
• פורמט: ספר
• יצא לאור: BMC, 2019-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract Background Intramuscular myxoma (IM) is a hypocellular benign soft tissue neoplasm characterized by abundant myxoid stroma and occasional hypercellular areas. These tumors can, especially on biopsy material, be difficult to distinguish from low-grade fibromyxoid sarcoma or low-grade myxofib...