How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up

• المؤلفون الرئيسيون: C. Bassand (مؤلف), L. Benabed (مؤلف), J. Freitag (مؤلف), J. Verin (مؤلف), F. Siepmann (مؤلف), J. Siepmann (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2022-12-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The aim of this study was to better understand the potential impact of partial vs. complete renewal of the bulk fluid during drug release measurements from poly (lactic-co-glycolic acid) (PLGA)-based implants. A "standard experimental set-up", in which the implants were directly exposed to...