Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells

• Main Authors: Matyunina Lilya V (Author), Walker L DeEtte (Author), Bowen Nathan J (Author), Logani Sanjay (Author), Totten Kimberly A (Author), Benigno Benedict B (Author), McDonald John F (Author)
• Format: Book
• Published: BMC, 2009-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Accumulating evidence suggests that somatic stem cells undergo mutagenic transformation into cancer initiating cells. The serous subtype of ovarian adenocarcinoma in humans has been hypothesized to arise from at least two possible cl...