Oxidative Stress Induced Damage and Early Senescence in Preterm Placenta

• Main Authors: Yudianto Budi Saroyo (Author), Noroyono Wibowo (Author), Rima Irwinda (Author), Ani Retno Prijanti (Author), Evy Yunihastuti (Author), Saptawati Bardosono (Author), Sofie Rifayani Krisnadi (Author), Putri Indah Permata (Author), Stephanie Wijaya (Author), Victor Prana Andika Santawi (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Senescent cells have been demonstrated to release High Mobility Group Box 1 (HMGB1) which induces labor through an inflammatory pathway. This research is aimed at demonstrating whether telomere shortening, proinflammatory HMGB1, and oxidative damage marker 8-OHdG play a role in the pla...