Oral administration of sitagliptin activates CREB and is neuroprotective in murine model of brain trauma

• Hoofdauteurs: Brian Dellavalle (Auteur), Gitte Stokvad Brix (Auteur), Birgitte Brock (Auteur), Michael Gejl (Auteur), Jørgen Rungby (Auteur), Agnete Larsen (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2016-12-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Introduction: Traumatic brain injury is a major cause of mortality and morbidity. We have previously shown that the injectable glucagon-like peptide-1 (GLP-1) analogue, liraglutide, significantly improved the outcome in mice after severe traumatic brain injury (TBI). In this study we are interested...