A randomized crossover study comparing different tacrolimus formulations to reduce intrapatient variability in tacrolimus exposure in kidney transplant recipients

• Main Authors: Kim L. W. Bunthof (Author), Linda Al‐Hassany (Author), Gizal Nakshbandi (Author), Dennis A. Hesselink (Author), Ron H. N. vanSchaik (Author), Marc A. G. J. ten Dam (Author), Marije C. Baas (Author), Luuk B. Hilbrands (Author), Teun vanGelder (Author)
• Format: Book
• Published: Wiley, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract A high intrapatient variability (IPV) in tacrolimus exposure is a risk factor for poor long‐term outcomes after kidney transplantation. The main objective of this trial was to investigate whether tacrolimus IPV decreases after switching patients from immediate‐release (IR)‐tacrolimus to eit...