In vitro and in vivo efficacy of Monepantel (AAD 1566) against laboratory models of human intestinal nematode infections.

• Główni autorzy: Lucienne Tritten (Autor), Angelika Silbereisen (Autor), Jennifer Keiser (Autor)
• Format: Książka
• Wydane: Public Library of Science (PLoS), 2011-12-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

BACKGROUND: Few effective drugs are available for soil-transmitted helminthiases and drug resistance is of concern. In the present work, we tested the efficacy of the veterinary drug monepantel, a potential drug development candidate compared to standard drugs in vitro and in parasite-rodent models...