Combined metabolomics and transcriptomics analysis of rats under neuropathic pain and pain-related depression

• Main Authors: Caiyun Xi (Author), Liqiong He (Author), Zhifeng Huang (Author), Jianxi Zhang (Author), Kailu Zou (Author), Qulian Guo (Author), Changsheng Huang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuropathic pain often leads to negative emotions, which in turn can enhance the sensation of pain. This study aimed to investigate the molecular mechanisms mediating neuropathic pain and negative emotions. Chronic constriction injury (CCI) rats were used as model animals and behavioral tests were c...