Behavior of Regular Insulin in a Parenteral Nutrition Admixture: Validation of an LC/MS-MS Assay and the In Vitro Evaluation of Insulin Glycation

• Principais autores: Heloise Henry (Autor), Jean-François Goossens (Autor), Mostafa Kouach (Autor), Damien Lannoy (Autor), David Seguy (Autor), Thierry Dine (Autor), Pascal Odou (Autor), Catherine Foulon (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-05-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Parenteral-nutrition (PN)-induced hyperglycemia increases morbidity and mortality and must be treated with insulin. Unfortunately, the addition of insulin to a ternary PN admixture leads to a rapid decrease in insulin content. Our study's objective was to determine the mechanistic basis of insu...