Path4Drug: Data Science Workflow for Identification of Tissue-Specific Biological Pathways Modulated by Toxic Drugs

• Autors principals: Barbara Füzi (Autor), Jana Gurinova (Autor), Henning Hermjakob (Autor), Gerhard F. Ecker (Autor), Rahuman Sheriff (Autor)
• Format: Llibre
• Publicat: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The early prediction of drug adverse effects is of great interest to pharmaceutical research, as toxicity is one of the leading reasons for drug attrition. Understanding the cell signaling and regulatory pathways affected by a drug candidate is crucial to the study of drug toxicity. In this study, w...