The Ambivalent Role of miRNAs in Carcinogenesis: Involvement in Renal Cell Carcinoma and Their Clinical Applications

• Main Authors: Federica Spadaccino (Author), Margherita Gigante (Author), Giuseppe Stefano Netti (Author), Maria Teresa Rocchetti (Author), Rossana Franzin (Author), Loreto Gesualdo (Author), Giuseppe Castellano (Author), Giovanni Stallone (Author), Elena Ranieri (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The analysis of microRNA (miRNAs), small, non-coding endogenous RNA, plays a crucial role in oncology. These short regulatory sequences, acting on thousands of messenger RNAs (mRNAs), modulate gene expression at the transcriptional and post-transcriptional level leading to translational repression o...