Enhancement of Cognitive Function by Andrographolide-Loaded Lactose β-Cyclodextrin Nanoparticles: Synthesis, Optimization, and Behavioural Assessment

• Main Authors: Debashish Paramanick (Author), Kagithala Naga Rani (Author), Vijay Kumar Singh (Author), Parakh Basist (Author), Rahmuddin Khan (Author), Jameel H. Al-Tamimi (Author), Omar M. Noman (Author), Mansour N. Ibrahim (Author), Abdulsalam Alhalmi (Author)
• Format: Book
• Published: MDPI AG, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigates whether Andrographolide-loaded Lactose β-Cyclodextrin (ALN-βCD) nanoparticles enhance cognitive function, particularly spatial learning and memory. The successful conjugation of lactose to β-cyclodextrin was confirmed via 1H NMR spectroscopy, facilitating neuronal cell entry....