Garmultin-A Incites Apoptosis in CB3 Cells Through miR-17-5p by Attenuating Poly (ADP-Ribose) Polymerase-1

• Main Authors: Jianfei Qiu (Author), Li Chen (Author), Jue Yang (Author), Krishnapriya M. Varier (Author), Babu Gajendran (Author), Yao Yao (Author), Wuling Liu (Author), Jingrui Song (Author), Qing Rao (Author), Qun Long (Author), Chunmao Yuan (Author), Xiaojiang Hao (Author), Yanmei Li (Author)
• Format: Book
• Published: SAGE Publishing, 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Leukemia accounts for a large number of deaths, worldwide, every year. Treating this ailment is always a challenging job. Recently, oncogenic miRNA leading to apoptosis are highly promising targets of many natural products. In this study, Garmultin-A (GA), isolated from the bark of Garcin...