Protein O-Glycosylation Induces Collagen Expression and Contributes to Diabetic Cardiomyopathy in Rat Cardiac Fibroblasts

• Autors principals: Yuka Kohda (Autor), Miwa Kanematsu (Autor), Tatsuji Kono (Autor), Fumio Terasaki (Autor), Takao Tanaka (Autor)
• Format: Llibre
• Publicat: Elsevier, 2009-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Diabetic cardiomyopathy may be accompanied by myocardial fibrosis. We have previously reported that cardiac fibrosis and protein O-glycosylation are elevated in diabetes. In this study, we examined if the hexosamine biosynthesis pathway (HBP) was involved with collagen expression in rat cardiac fibr...