Fast Green FCF Attenuates Lipopolysaccharide-Induced Depressive-Like Behavior and Downregulates TLR4/Myd88/NF-κB Signal Pathway in the Mouse Hippocampus

• Main Authors: Jing Yang (Author), Rongjun Liu (Author), Fan Lu (Author), Fang Xu (Author), Jinwei Zheng (Author), Zhao Li (Author), Wei Cui (Author), Chuang Wang (Author), Junfang Zhang (Author), Shujun Xu (Author), Wenhua Zhou (Author), Qinwen Wang (Author), Junping Chen (Author), Xiaowei Chen (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Depression is a common neuropsychiatric disorder and new anti-depressive treatments are still in urgent demand. Fast Green FCF, a safe biocompatible color additive, has been suggested to mitigate chronic pain. However, Fast green FCF's effect on depression is unknown. We aimed to investigate Fa...