DIAGNOSTIC VALUE OF STUDYING THE LEVELS OF PRO- AND ANTI-INFLAMMATORY CYTOKINES OF THE IMMUNE SYSTEM IN PATIENTS WITH BREAST CANCER
The diagnostic value of the serum levels of proinflammatory (TNF-α, IL-1β, IL-6, and IFN-γ) and anti-inflammatory (IL-4 and IL-10) cytokines of the immune system was studied in 54 patients with breast cancer (BC). Analysis identified the increased concen- trations of proinflammatory cytokines, such...
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Published: |
ABV-press,
2014-09-01T00:00:00Z.
|
| Subjects: | |
| Online Access: | Connect to this object online. |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The diagnostic value of the serum levels of proinflammatory (TNF-α, IL-1β, IL-6, and IFN-γ) and anti-inflammatory (IL-4 and IL-10) cytokines of the immune system was studied in 54 patients with breast cancer (BC). Analysis identified the increased concen- trations of proinflammatory cytokines, such as IL-1β, TNF-α, and IL-6, in the peripheral sera of BC patients.Analysis of anti-inflammatory cytokines in the peripheral sera of patients with BC also revealed a significant increase in the values of IL-4 and IL-10. The findings suggest that there is imbalance between cellular and humoral immunity factors, the study of which will be an important diagnostic criterion for BC. |
|---|---|
| Item Description: | 1994-4098 1999-8627 10.17650/1994-4098-2009-0-3-4-49-52 |