Paradoxical Effect of 2,3-Dimercapto-1-propanesulfonic Acid (DMPS) on Enhancing Antitumor Activity of Cisplatin in Ascites Sarcoma 180 Cells

We investigated the enhancing effect of two metal-chelating compounds, 2,3-dimercapto-1-propanesulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA), on the antitumor activity of cisplatin (CDDP). In the in vivo experiments, DMPS showed a clear synergistic effect and significantly enhance...

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Main Authors: Toshihiro Sato (Author), Migiwa Okubo (Author), Kohei Sawaki (Author), Hiroshi Maehashi (Author), Mitsuru Kawaguchi (Author)
Format: Book
Published: Elsevier, 2010-01-01T00:00:00Z.
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