Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway

• Main Authors: Tianyuan Jiang (Author), Ran Niu (Author), Qian Liu (Author), Yuhan Fu (Author), Xiaoying Luo (Author), Tao Zhang (Author), Baoqi Wu (Author), Juan Han (Author), Yang Yang (Author), Xiaolan Su (Author), Jiande D. Z. Chen (Author), Gengqing Song (Author), Wei Wei (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The goal of the study was to analyze whether WJP can alleviate visceral hypersensitivity in IBS-D model rats. In this study, 36 Sprague-Dawley (SD) rats aged 4 weeks old were randomly divided into two groups: the model group (n = 27) and the control group (n = 9). The rat model of IBS-D was establis...