The Biological Functions and Clinical Applications of Integrins in Cancers

• Main Authors: Chao-yue Su (Author), Jing-quan Li (Author), Ling-ling Zhang (Author), Hui Wang (Author), Feng-hua Wang (Author), Yi-wen Tao (Author), Yu-qing Wang (Author), Qiao-ru Guo (Author), Jia-jun Li (Author), Yun Liu (Author), Yan-yan Yan (Author), Jian-ye Zhang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Integrins are the adhesion molecules and receptors of extracellular matrix (ECM). They mediate the interactions between cells-cells and cells-ECM. The crosstalk between cancer cells and their microenvironment triggers a variety of critical signaling cues and promotes the malignant phenotype of cance...