Vortioxetine Differentially Modulates MK-801-Induced Changes in Visual Signal Detection Task Performance and Locomotor Activity

• Main Authors: Todd M. Hillhouse (Author), Christina R. Merritt (Author), Douglas A. Smith (Author), Manuel Cajina (Author), Connie Sanchez (Author), Joseph H. Porter (Author), Alan L. Pehrson (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Attention impairment is a common feature of Major Depressive Disorder (MDD), and MDD-associated cognitive dysfunction may play an important role in determining functional status among this patient population. Vortioxetine is a multimodal antidepressant that may improve some aspects of cognitive func...