Effects of nimesulide on pain and on synovial fluid concentrations of sp, il-6, and il-8 in patients with knee osteoarthritis: comparison with celecoxib

• Main Authors: Mauro Bianchi (Author), Paola Sacerdote (Author), Silvia Franchi (Author), Paolo Ferrario (Author), Patrizia Balzarini (Author), Marco Broggini (Author)
• Format: Book
• Published: Publiediting, 2006-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We compared the effects of two NSAIDs, nimesulide (100 mg twice a day) and celecoxib (200 mg once a day), on pain and synovial fluid concentrations of inflammatory pain mediators in twenty patients with knee OA with joint effusion in a controlled, double-blind, parallel group study. Plasma and synov...