Role of Nitric Oxide, Nitric Oxide Synthase, Soluble Guanylyl Cyclase, and cGMP-Dependent Protein Kinase I in Mouse Stem Cell Cardiac Development

Role of Nitric Oxide, Nitric Oxide Synthase, Soluble Guanylyl Cyclase, and cGMP-Dependent Protein Kinase I in Mouse Stem Cell Cardiac Development

Introduction and Aim. Nitric oxide (NO) can trigger cardiac differentiation of embryonic stem cells (ESCs), indicating a cardiogenic function of the NO synthetizing enzyme(s) (NOS). However, the involvement of the NO/NOS downstream effectors soluble guanylyl cyclase (sGC) and cGMP activated protein...

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Main Authors: Valentina Spinelli (Author), Alessia Vona (Author), Francesca Corti (Author), Lorenzo Diolaiuti (Author), Matteo Zanardelli (Author), Laura Sartiani (Author), Paola Failli (Author)
Format: Book
Published: Hindawi Limited, 2016-01-01T00:00:00Z.
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3rd Floor Main Library

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