Expressions of TWIST1 and CD105 markers in colorectal cancer patients and their association with metastatic potential and prognosis

• Main Authors: Fahimeh Fattahi (Author), Leili Saeednejad Zanjani (Author), Somayeh Vafaei (Author), Zohreh Habibi Shams (Author), Jafar Kiani (Author), Marzieh Naseri (Author), Elmira Gheytanchi (Author), Zahra Madjd (Author)
• Format: Book
• Published: BMC, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background TWIST1 and CD105, which contribute to tumor malignancy, are overexpressed in cancers. Accordingly, TWIST1 enhances epithelial-to-mesenchymal transition (EMT) and promotes the formation of cancer stem cells (CSCs). Also, CD105 is a neoangiogenesis marker in endothelial cells, whic...