Population pharmacokinetic analysis of dupilumab in adult and adolescent patients with asthma

• Váldodahkkit: Li Zhang (Dahkki), Yue Gao (Dahkki), Meng Li (Dahkki), Christine Xu (Dahkki), John D. Davis (Dahkki), Vanaja Kanamaluru (Dahkki), Qiang Lu (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Wiley, 2021-08-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Abstract A population pharmacokinetic model was developed using data from healthy subjects and patients with moderate‐to‐severe asthma receiving intravenous or subcutaneous dupilumab doses. A total of nine phase I to phase III studies were pooled (202 healthy subjects and 1912 patients with asthma i...