Population pharmacokinetic analysis of dupilumab in adult and adolescent patients with asthma

• Prif Awduron: Li Zhang (Awdur), Yue Gao (Awdur), Meng Li (Awdur), Christine Xu (Awdur), John D. Davis (Awdur), Vanaja Kanamaluru (Awdur), Qiang Lu (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Wiley, 2021-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Abstract A population pharmacokinetic model was developed using data from healthy subjects and patients with moderate‐to‐severe asthma receiving intravenous or subcutaneous dupilumab doses. A total of nine phase I to phase III studies were pooled (202 healthy subjects and 1912 patients with asthma i...